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0.05). DATA CONCLUSION I-mIBG avidity and ADC values are complementary noninvasive biomarkers of therapeutic response in HR-NB. 4. 3. 3.Osteopetrosis is a rare hereditary bone development disorder caused by osteoclast dysfunction, which increases bone density. Although few studies have investigated cardiovascular disease in osteopetrosis, sternotomy outcomes in this condition are unclear. We report the case of a patient with osteopetrosis and severe mitral regurgitation. A 63-year-old woman with exertional dyspnea had regurgitant systolic murmur