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Successful telehealth antimicrobial stewardship models should be explored further as a means to provide optimal patient care.Mesophyll conductance (gm) is a crucial leaf trait contributing to photosynthetic rate (AN). Plant domestication typically leads to an enhancement of AN that is often associated with profoundly anatomical modifications but it is unclear which of these structural alterations influence gm. We analyzed the implication of domestication on leaf anatomy and its effect on gm in 26 wild and 31 domesticated cotton genoty