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Medications For ADHD and Anxiety Medications that treat ADHD generally work well for anxiety too. The stimulants methylphenidate and amphetamine increase the levels of certain neurotransmitters in the brain. Antidepressants and nonstimulants like atomoxetine can also aid. In some cases stimulant medications can exacerbate anxiety symptoms. If that's the case, your doctor could prescribe a different medication or switch to a different one altogether. Stimulants Stim