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Our study revealed that the right FAT can be divided into three segments and that its posterior segment is related to acute phase motor function. The Madeira River (Amazon Basin) has been impacted by activities related to artisanal and small-scale gold mining (ASGM), deforestation and burning (for timber, agriculture, and hydroelectric dam projects). All these activities contribute to environmental mercury (Hg) release and cycling into the Amazon ecosystem and thus to changing lifestyles. We assessed exposure to total and MeHg in two sm