https://www.selleckchem.com/pr....oducts/eidd-1931.htm
01) the adiponectin level, in HFD induced obese rats. The down-regulation of the adipokine secretion significantly increased (p less then 0.01) the hepatic and muscle glycogen synthase activity and suppressed the hepatic gluconeogenesis activity via activating the insulin receptor-mediated PI3K/AKT/GLUT insulin signaling pathway thereby improving the insulin sensitivity. On the other hand calcium deficient HFD (0.25% Ca) accelerated the risk of insulin resistance (IR) due to its inability to improve insulin sensitivity by activating t
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