https://www.selleckchem.com/ph....armacological_epigen
The diameter- or area-reduction ratio measured from coronary angiography, commonly used in clinical practice, is not accurate enough to represent the functional significance of the stenosis, i.e., the pressure drop across the stenosis. We propose a new zero-dimensional model for the pressure drop across the stenosis considering its geometric characteristics and flow rate. To identify the geometric parameters affecting the pressure drop, we perform three-dimensional numerical simulations for thirty-three patient-specific coron