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The modern era of intervention in necrotizing pancreatitis (NP) has seen a significant paradigm shift toward minimally invasive approaches as initial therapy. This video outlines the critical steps of OPD for NP. A 69-year-old female with acute biliary NP underwent OPD for NP after 12-weeks of medical management. Her postoperative course was uncomplicated, and she was discharged home on postoperative day seven. The patient recovered uneventfully. Operative pancreatic debridement (OPD), now considered the final step in the modern treatment