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ents undergoing neuraxial anaesthesia are at decreased risk for postoperative complications, perioperative blood transfusions, and extended length of stay. Prospective controlled trials should be conducted to verify these findings.In the present study we investigated the isotope effects associated with water loss from closed low-density polyethylene (LDPE) bottles via diffusion at temperatures between 4 and 60 °C. While at low temperatures (4 and 10 °C) no substantial diffusional loss of water was observed within storage time, a pronounced lo