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Finally, we will describe recent human brain imaging studies that provide evidence of a role for these hypothalamic regions in setting resting sympathetic drive and their potential role in conditions such as hypertension.The zona incerta (ZI) is a large structure made of four neurochemically defined regions (at least, in rodents). It is globally involved in complex connections with telencephalic and brainstem centers. In this work, we focus on some of the anatomical links this structure develops with the cerebral cortex and the tectum. W
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