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The median number of samples collected was 4 (range 2-9). The results were diagnostic in 54 cases (94.7%, 95% confidence interval [CI] 88.7-100.. There were 12 (21%, 95% CI 10.1-31.9) patients with minor complications and 2 (3.5%, 95% CI 0.0-8.4) with major complications (2 splenic bleeds requiring embolization, no splenectomy, or deaths). No variables (needle size, lesion size, and number of passes) were associated with complication rate. CONCLUSION Percutaneous image-guided biopsy of the spleen at a single tertiary care institution dem
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