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ADHD Treatments For Adults Stimulants like methylphenidate and amphetamine, are the first treatment most doctors recommend. They help balance the levels of two chemical messengers in the brain. Atomoxetine (Strattera) and antidepressants also may help reduce symptoms, but they operate slower. Psychotherapy, like cognitive behavioral therapy can help adults develop techniques to improve organization and planning. Psychotherapy and coaching are also effective in improving social fun