https://www.selleckchem.com/pr....oducts/5-ethynylurid
These variant-to-function maps reveal an enhancer that contains an IBD risk variant and that regulates the expression of PPIF to alter the membrane potential of mitochondria in macrophages. Our study reveals principles of genome regulation, identifies genes that affect IBD and provides a resource and generalizable strategy to connect risk variants of common diseases to their molecular and cellular functions.Critical periods-brief intervals during which neural circuits can be modified by activity-are necessary for proper neural
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