https://www.selleckchem.com/pr....oducts/kb-0742-dihyd
Circular RNAs (circRNAs) are widespread endogenous transcripts lacking 5'-caps and 3'-polyadenylation tails. Their closed-loop structure confers exonuclease resistance and extreme stability. CircRNAs play essential roles in various diseases, including diabetes. Diabetic nephropathy (DN) is the leading cause of end-stage kidney disease and is one of the most common complications of diabetes. CircRNAs are key in DN and therefore important for understanding DN pathophysiology and developing new therapeutic strategies. In th