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001, 0.001, = 0.031, respectively). After controlling for baseline risk factors, we found that the carrier of the -4 allele of ALR (AC)n polymorphism had a higher risk of diabetic retinopathy and diabetic nephropathy ( 0.001). The homozygosity for the -4 allele was found to be associated with diabetic microangiopathy. Our results showed that ALR (AC)n gene polymorphism in Iranian patients with type 2 diabetes independently, predispose retinal, renal and neural microvascular to diabetic complications. Our results showed that ALR (AC)n ge