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To evaluate whether orthostatic hypotension (OH) or supine hypertension (SH) is associated with brain atrophy and white matter hyperintensities (WMH), we analyzed clinical and radiological data from a large multicenter consortium of patients with Parkinson's disease (PD) and dementia with Lewy bodies (DL. Supine and orthostatic blood pressure and structural magnetic resonance imaging data were extracted from PD and DLB patients evaluated at eight tertiary-referral centers in the USA, Canada, Italy, and Japan. OH was defined as a systo
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