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Treatment of Add in Adults Treatment of add in adults usually involves a combination of medications, life skills training, and psychotherapy. Most patients respond well to stimulant medicines like methylphenidate (Ritalin) and amphetamines such as Lisdexamphetamine (Adderall) or extended-release mixed amphetamine salts (Adderall XR). Stimulants can increase blood pressure and heart rate. Nonstimulants, such as atomoxetine and bupropion, also help to r