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Solid-phase extraction with gliadin- and Emdogain-coated Sepharose revealed a gliadin cross-reactive central region and a putative conformation-dependent, apparently non-cross-reactive N-terminal region. High IgA anti-amelogenin reactivity may interfere with normal amelogenesis by inhibiting amelogenin self-assembly, amelogenin-hydroxyapatite interaction, and/or enzymatic degradation. © 2020 The Authors. Eur J Oral Sci published by John Wiley Sons Ltd.Cilia are microtubule-based, cell-surface projections whose machinery is evoluti