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The longitudinal relaxivity of SPNs increases stepwise in the above two processes. The size-switchable polyprodrug nanoparticles exhibit remarkable tumor penetration and noteworthy tumor inhibition in vitro and in vivo, which are promising for endogenously activated precision diagnostics and therapy.Nanostructured polymer interfaces can play a key role in addressing urgent challenges in water purification and advanced separations. Conventional technologies for mercury remediation often necessitate large energetic inputs, produce significant secondary waste,