https://www.selleckchem.com/products/Estrone.html
I has an expected value of 0.798 and, assuming independent site characteristics, a variance of 0.363/k, where k is the number of site characteristics being balanced. Simulations indicated that the properties of I are robust under varying covariate circumstances as long as k is greater than 3 and the covariates are not too highly inter-correlated. We recommend that values of I below the 10th percentile indicate sufficient overall site balance in CCRs. Definitions of acceptable randomizations might also include individual covariate criter
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