https://www.selleckchem.com/pr....oducts/pin1-inhibito
The biological nature of temporomandibular joint (TMJ) featuring adaptive remodeling allows for TMJ structural changes in response to external stimuli, including alterations in occlusion and in mandibular posture. Correlative susceptibility exists between malocclusions and TMJ disorders (TMD), evidenced by high incidence of TMD coinciding with skeletal originated malocclusion with facial prognathsim (Angle Class I skeletal II high angle). Clinical manifestations include markedly retruded mandible together with increased ove
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