https://www.selleckchem.com/pr....oducts/Camptothecine
Purpose We studied the expression of urotensin II (UII) and its relationships with markers of pyroptosis in preeclampsia. Methods 48 pregnant subjects were recruited consisting of 28 severe preeclampsia pregnancies (SPE) and 20 healthy pregnancies. We detected expressions of UII and markers of pyroptosis such as NLR-family pyrin domain (PYD)-containing 3 (NLRP-3), caspase-1/4/5, interleukin-1β (IL-1β), and gasdermin D (GSDMD) in placentas of patients with SPE and healthy pregnancies. Results SPE group have higher expression of UII