https://www.selleckchem.com/pr....oducts/pf-07265807.h
Inhibition of TF / heparanase interaction may represent a new target for attenuating coagulation, cancer and inflammation.The story of heparanase (HPSE) in viral infection has roots in the longstanding connection between heparan sulfate (HS) and a large number of viruses. As a major viral attachment and entry receptor present on the cell surface, HS serves as the first point of contact between a virus particle and its target host cell. Likewise, direct regulation of HS levels on the cell surface by HPSE enzymatic activity dictates t