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Main Results The sensitivity and specificity of the TRS for low-risk patients against the moderate-risk and high-risk patients were 97% (95% CI 91-99%) and 16% (95% CI 11-23%), respectively. These results corresponded to a positive likelihood ratio of 1.15 (95% CI 1.07-1.24) and a negative likelihood ratio of 0.20 (95% CI 0.06-0.65). CONCLUSIONS In this study, the TRS showed high sensitivity, making it useful in identifying patients at low risk of QTc interval prolongation. However, the low specificity of the TRS suggests that it should n