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90; P less then 0.001), plasma levels of lactate dehydrogenase (HR, 1.01; P less then 0.001), hemoglobin levels (HR, 0.80; P = 0.013), whole-body SUVmax (HR, 1.14; P less then 0.001), the number of 18F-FDG-avid metastases (HR, 1.08; P less then 0.001), whole-body metabolic tumor volume (HR, 1.86; P less then 0.001), and TLG (HR, 1.84; P less then 0.001). On multivariable analysis with stepwise variable selection, hemoglobin levels (HR, 0.81; P = 0.013) and whole-body TLG (HR, 1.88; P less then 0.001) were independently associated with O