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Decoupling water use from economic development is a fundamental strategy to improve environmental quality from the source. It can promote economic growth while reducing water use and water pollution. This article uses water footprint theory to calculate the relevant indicators of the water quantity footprint and water quality footprint of the Northwest arid region between 1997 and 2017. This paper not only comprehensively consider the impact rate of economic development on water resource consumption and water pollution, but also analyze