https://atpase-signaling.com/i....ndex.php/constitutio
Literature precedents coupled with our experience rendered us with several insights that resulted in the addition of chemically diverse linkers and hydroxamic acid (zinc-binding theme) due to the fact other the different parts of HDAC inhibitory pharmacophore. Using this envisionment and quality, donepezil-based HDAC inhibitory adducts were furnished and exhaustively investigated with regards to their anti-GBM efficacy. Resultantly, a magnificently powerful HDAC in