https://www.selleckchem.com/pr....oducts/envonalkib.ht
BACKGROUND Hepatocyte-like cells (iHEPs) generated by transcription factor-mediated direct reprogramming of somatic cells have been studied as potential cell sources for the development of novel therapies targeting liver diseases. The mechanisms involved in direct reprogramming, stability after long-term in vitro expansion, and safety profile of reprogrammed cells in different experimental models, however, still require further investigation. METHODS iHEPs were generated by forced expression of Foxa2/Hnf4a in mouse mesenchymal stroma
Like
Comment
Share
