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A complete of 3,403 breathing samples including sputum and endotracheal aspirates had been prepared and antibiotic drug resistance structure had been determined after medical Laboratory traditional Institute recommendations. Clients' information had been obtained after informed permission. Growth of Gram-negative bacteria was 210 (6.17%). 83(39.52%) were Klebsiella pneumoniae accompanied by Escherichia coli, Pseudomonas aeruginosa, Acinetobacter types, Klebs