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Background Dimethyl fumarate (DMF) is the active ingredient of Skilarence™ and Tecfidera™ which are used for the treatment of psoriasis and multiple sclerosis, respectively. Various immunomodulatory mechanisms of action have been identified for DMF; however, it is still unclear what effects DMF exerts in vivo in psoriasis patients. Aim In this study we examined the effects of DMF, both in vivo and in vitro, on T cells which play a key role in the pathogenesis of psoriasis. Methods The frequency of T cell subsets was examined by flow cyto
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