https://www.selleckchem.com/pr....oducts/polybrene-hex
Background Recent developments in literature on sample size calculations for time-to-event outcomes involve assumption of Weibull distributed times. These methods require a point estimate of the Weibull shape parameter obtained from historical studies. However, very limited guidance exists in published literature to assess how reliable this point estimate is when it is obtained from published results of a historical study. Methods We conduct simulations to assess how accurate and reliable the point estimate of