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ADHD Treatment For Adults The stimulants methylphenidate and amphetamine help boost levels of certain brain chemicals. Nonstimulants like atomoxetine or antidepressants are slower than stimulants, however, they can be just as beneficial. Comorbid conditions can affect the response of ADHD medication. Physicians should address the most severe symptom of any comorbid disorder first, and then check to see if the ADHD symptoms improve. Medication Medication is the