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quantity.This is an editorial report of the supplements to BMC Bioinformatics that includes 6 papers selected from the BIOCOMP'19-The 2019 International Conference on Bioinformatics and Computational Biology. These articles reflect current trend and development in bioinformatics research. About 50% of all hospitalized fragility fracture cases in older Americans are hip fractures. Approximately 3/4 of fracture-related costs in the USAare attributable to hip fractures, and these are mostly covered by Medicare. Hip fracture patients with