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PLGA, a FDA accepted polymer, established fact into the literary works to make films or nanoparticles that may load, protect, and provide drug particles; however, its incompatibility with specific medications (because of hydrophilicity or charge repulsion interactions) restricts its use. Incorporating PLGA or other polymers such polycaprolactone with other safe and positively-charged particles, such as for instance chitosan, was desired to produce hybrid methods which can be much more f