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80, p 0.01). Patients with RGS grades 2-3 had a significantly higher risk for development of RP (relative risk (RR) 2.4, 95% CI 1.6-3.7, p 0.01) and RP symptoms within 8weeks after RT (RR 4.8, 95% CI 1.3-17.6, p 0.01) compared to RGS grades 0-1. The specificity and sensitivity of the RGS grades 2-3 in predicting symptomatic RP was 100% (95% CI 80.5-100%) and 45.4% (95% CI 24.4-67.8%), respectively. Increase in RGS severity correlated to mean lung dose and the percentage of the total lung volume receiving 5Gy. The RGS is a
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