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For ADHD - What Are the Side Effects? Many people who suffer from ADHD experience improvements in their symptoms by taking medication. Each person's reaction to drugs is different, and side effects can be a problem. Methylphenidate is a stimulant. It works by increasing levels of a chemical within the brain that helps control attention and behavior. Stimulant medications Stimulants enhance attention and concentration in 70 to 80% of children and adults who take them. They alter neurotransmitters such as norepinephrine and dopamine in the brain. They usually cause
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