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similarity coefficient and Hausdorff distance. Note that the proposed method is not limited to the segmentation of complex lung tumors but also performs in different modalities of medical image segmentation. In previous work, we demonstrated that mixed electron-photon radiation therapy (MBRT) produces treatment plans with improved normal tissue sparing and similar target coverage, when compared to photon-only plans. The purpose of this work was to validate the MBRT delivery process on a Varian TrueBeam accelerator and laying the groundwo