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It is highly anticipated that the large macrocyclic host cavity-triggered large-guest encapsulation strategy in this work will provide a convenient and efficient method for designing supramolecular porphyrin dyes, thus broadening the diagnosis and imaging application in cells and microorganisms.A simple approach to fabricating hydrogel-based DNA microarrays is reported by physically entrapping the rolling circle amplification (RCA) product inside printable in situ gelling hydrazone cross-linked poly(oligoethylene glycol methacrylate) h