https://www.selleckchem.com/pr....oducts/Nanchangmycin
In order to facilitate the passage of EC33 through the blood-brain barrier, the two molecules of EC33 were linked by a disulfide bridge to form a prodrug called RB150. RB150, later renamed as QGC001 or firibastat, was found to be effective in animal models and well-tolerated when used in healthy participants. Firibastat was found to be safe and effective in phase 2 trials, and is now planned to undergo a phase 3 trial. Firibastat has the potential to be groundbreaking in the management of resistant hypertension.Elevated cholestero
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