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001), the time to first analgesic request ( = .001), and ketorolac administration times ( = .01) were significantly different between 3 groups. Finally, no complication was reported regarding postoperative nausea and vomiting. Given the notable efficacy of tramadol in reducing pain after hemorrhoidectomy and its minor side effects, this medication is suggested as an effective topical anesthetic to decrease pain after hemorrhoidectomy. Given the notable efficacy of tramadol in reducing pain after hemorrhoidectomy and its minor side effec