https://www.selleckchem.com/pr....oducts/gsk3368715.ht
FDG-PET hypermetabolism can be observed in mild cognitive impairment (MCI), but the link to primary pathologies of Alzheimer's diseases (AD) including amyloid and tau is unclear. Using voxel-based regression, we assessed local interactions between amyloid- and tau-PET on spatially matched FDG-PET in 72 MCI patients. Control groups included cerebrospinal fluid biomarker characterized cognitively normal (CN, n = 7 and AD dementia subjects (n = 95). In MCI, significant amyloid-PET by tau-PET interactions were found in frontal, lateral
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