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INTRODUCTION We used road crashes between vehicles and two-wheelers from Yinzhou District Ningbo in 2011-2015 from the China In-depth Accident Study (CIDAS) as sample cases. The risk factors of different injury severity grades were analyzed. METHOD The classification tree model was used to screen the possible interaction items, and the corresponding regression model was constructed according to the results of the tree model to explore the influencing factors of cyclist injury. RESULTS The road types, weather types, gender, age of the ri