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Shrinkage stress, DC% and VH of both composite resins significantly increased with the conventional 20 s light curing protocol (p less then 0.05). Light curing conventional composite resin with the fast high-intensity (3-s) curing protocol resulted in inferior results for some important material properties.De novo variants (DNVs) are critical to the treatment of neurodevelopmental disorders (NDDs). However, effectively identifying candidate genes in small cohorts is challenging in most NDDs because of high genetic heterogeneity. We hyp