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EA at LR3 increases the excitability of the contralateral cerebral sensory cortex (lower extremity area), but has no effect on the adjacent sensory cortex (genital area). To observe the clinical efficacy of silver needle heat conduction therapy combined with loxoprofen sodium patch in the treatment of knee osteoarthritis (KOA). A total of ninety-two patients with KOA were randomly and equally divided into loxoprofen sodium group and silver needle heat conduction therapy + loxoprofen sodium (combination) group, with 46 cases in each grou