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Medical trials in dermatomyositis tend to be at the forefront with ongoing multicenter, international stage 3 medical trials. Proof-of-concept studies targeting the JAK/STAT path have also demonstrated very early guarantee in managing refractory dermatomyositis in adults and children. This review features that the future armamentarium of healing medicines will likely be larger and much more selective in managing different subgroups of myositis. Opioid use in the U.S. has increased considerably throughout the l