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Additionally, cleft of the soft palate, anterior open bite, severe crowding in the maxillary dental arch, and congenitally missing teeth occurred more frequently among AS patients. Multiple fusions between cervical vertebrae C2, C3, C5, and C6 were observed in the AS patients. LIMITATIONS Small sample size. CONCLUSIONS/IMPLICATIONS Our study shows that AS patients have more severe craniofacial and maxillofacial deformities than CS patients. © The Author(s) 2020. Published by Oxford University Press on behalf of the European Orthodonti