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Each group consisted of three wells. Group one with no treatment, team two included VCO, and group three added HVCO and then incubated for instantly. One well in each group had been added MMP-9, PDGF-BB, and TGF-β1 and incubated one hour. Eventually, expressions of MMP-9, PDGF-BB, and TGF-β1 had been detected utilizing immunocytochemistry method. RESULTS the outcomes of this study revealed that VCO and HVCO enhanced protein expressions of MMP-9, PDGF-BB, and TGF-β1. Portion of MMP-
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