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The endogenous ligands for GPCRs are extremely chemically diverse and can include ions, biogenic amines, nucleotides, peptides, and lipids. In this analysis, we proceed with the KonMari approach to better understand druggable lipid GPCRs. Initially, we a thorough tidying up of lipid GPCRs including receptors for prostanoids, leukotrienes, specialized pro-resolving mediators (SPMs), lysophospholipids, sphingosine 1-phosphate (S1P), cann