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0-day MACEs. In a prospective multisite US cohort, an initial hs-cTnT below the LOQ combined with a low-risk HEART score has a 99% NPV for 30-day MACEs. The 0/1-h hs-cTnT algorithm did not achieve an NPV 99% for 30-day MACEs when used alone or with a HEART score. Registration URL https//www.clinicaltrials.gov; Unique identifier NCT02984436. 99% for 30-day MACEs when used alone or with a HEART score. Registration URL https//www.clinicaltrials.gov; Unique identifier NCT02984436.Background Variation in outcomes by race/ethnicity in adults wi