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Instrumental vestibular assessment represents a pivotal tool to confirm the diagnosis of VN and BSVN. Ibuprofen, a well-known analgesic, is commonly used as a component of multimodal analgesic approach for postoperative pain. This systematic review and meta-analysis aimed to investigate whether single-dose preoperative intravenous ibuprofen can reduce postoperative pain and opioid consumption. Databases of PubMed/MEDLINE, Embase, Cochrane Library (CENTRAL), and Web of Science were searched to identify relevant studies published up to May 2020. Randomized co