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2 per 100 000 persons/year. Using GLM, the increment is statistically significant (P = 0.02). When compared to the last registry, the rate of increment had attenuated, with annual increment in crude incidence in the two periods for T1D less then 15 years changing from 4.3% to 3.5% (P = 0.02). CONCLUSIONS The incidence of T1D children increased significantly in the past two decades in Hong Kong, but the rate of increase had attenuated in recent years. This article is protected by copyright. All rights reserved. This article is protec